The Roxy Regional Theatre is Clarksville's main performing arts venue, housed in a 1942 Art Deco cinema building at 100 Franklin Street in the downtown historic district. The converted theatre stages professional productions year-round: musicals, dramas, Shakespeare, and locally-produced new work. Ticket prices are very reasonable compared to equivalent venues in larger cities.
The building exterior retains much of its original Art Deco character, with a distinctive marquee sign that is one of the most recognisable landmarks on the Clarksville streetscape. The theatre also offers stage-craft classes and runs an active educational programme in local schools.