Quinte West is about 175 kilometres east of Toronto on Highway 401 — roughly two hours by car in normal traffic. The town of Trenton has a VIA Rail station (Trenton Junction, on Telephone Road) served by trains on the Toronto–Ottawa–Montreal corridor; check the VIA Rail schedule as frequency is limited.
From Kingston, the drive west along Highway 401 takes about an hour. Greyhound and other intercity bus services stop in Trenton.