Souris is about 60 km east of Charlottetown along the Trans-Canada Highway and Route 2. The drive takes about 45 minutes. There is no scheduled bus service between Charlottetown and Souris; a car is effectively essential for visiting eastern PEI.
Charlottetown Airport (YYG) is the nearest airport, served by Air Canada and WestJet from Toronto, Montreal, and Halifax. The ferry to the Magdalen Islands (Îles-de-la-Madeleine) departs from Souris harbour; booking ahead is necessary in summer.