Big Timber is on Interstate 90 between Livingston and Billings, with easy road access from either direction. The nearest major airports are Bozeman Yellowstone International Airport to the west and Billings Logan International Airport to the east.
You need a car for the worthwhile sights outside town. Natural Bridge Falls is south of Big Timber on Secondary Highway 298, while Greycliff Prairie Dog Town is east of town near Greycliff.