Murfreesboro is 50 km southeast of Nashville on Interstate 24. Nashville International Airport is the nearest commercial airport, about 45 minutes by car. There is no passenger rail service to Murfreesboro itself.
By car from Nashville, take I-24 East to exit 78B (Broad Street) or 81A (Old Fort Parkway). The drive takes 40–50 minutes depending on traffic. Greyhound and other bus services connect Murfreesboro to Nashville and Chattanooga from the downtown transit centre.