The Coro Synagogue on Talavera Street is a former synagogue that now operates as a museum of Venezuelan Jewish history. Built in the 19th century by the Sephardic Jewish community that settled in Coro from Curaçao, it is one of the oldest synagogue buildings in South America. The building itself is modest — a colonial house adapted for religious use — but the museum inside documents the history of Venezuela's Jewish communities from the colonial period onward.
The adjacent Jewish Cemetery of Coro is separately notable as the oldest Jewish cemetery in continuous use in the Americas, with graves dating from the early 19th century. Both sites are within easy walking distance in the colonial centre.