By train: Sint-Niklaas has a direct train connection to both Ghent (20 minutes) and Antwerp (25 minutes), making it an easy day trip from either city. The station is about 10 minutes' walk north of the Grote Markt.
By car: Sint-Niklaas sits on the E17 motorway between Ghent and Antwerp. Exit at Sint-Niklaas; parking is available around the edge of the historic centre.