The nearest railway station is at Andora, two kilometres west of Laigueglia, on the line that runs along the Ligurian coast between Ventimiglia and Genoa. Local trains stop here every hour or so; the connection to Genoa takes about ninety minutes. A short bus or taxi covers the kilometres between the station and the village.
By car, the A10 motorway parallels the coast inland. The Andora exit drops you onto the SP1 coastal road, which carries you directly into Laigueglia in about ten minutes. Parking in the village proper is limited and metered in season; large free car parks at the western end of town (near the old salt warehouses) are the easier option in July and August.
The nearest airports are Nice (about two hours west by motorway) and Genoa (an hour east). Nice has more international connections; Genoa is closer and easier to drive from.