Catedral San Isidro Labrador is the main landmark in the city centre, facing the central park and giving San Isidro its obvious meeting point. It is a modest cathedral rather than an architectural showstopper, but it anchors the town's daily rhythm.
Come here to orient yourself, watch the square fill in the late afternoon, and understand the town as a regional centre rather than a tourist resort. Shops, banks, food, and buses are all close by.