By Air: Missoula Montana Airport (MSO) has direct flights from Seattle, Denver, Salt Lake City, Los Angeles, and other western hubs. The airport is about 5 km west of downtown; a taxi or rental car is the most practical option.
By Car: Missoula sits at the junction of I-90 (east-west) and US-93 (north-south). From Seattle it is about 7 hours; from Salt Lake City, 5.5 hours; from Spokane, 2.5 hours. Rental cars are available at the airport.
By Train: Amtrak's Empire Builder stops at Missoula once a day in each direction, connecting to Seattle and Chicago. The station is at 219 West Railroad Street, downtown. Travel times: Seattle, roughly 12 hours; Chicago, roughly 32 hours.