The Cashier's House is a three-storey stuccoed-brick Greek Revival building on State Street, dating from around 1839. It was built as the official residence of the cashier of the Bank of the United States and later served various governmental functions. The building's restrained classical proportions and fine detailing make it one of the better examples of early federal-era architecture in western Pennsylvania.
Together with the Old Customshouse next door and the rest of the State Street historic district, the Cashier's House is part of a concentration of early 19th-century civic architecture that is unusual for a city of Erie's size. Both buildings are on the National Register of Historic Places.