T'Air Nature Guyane is one of the handful of licensed receptive agencies in the territory — registered with Atout France as IM973180002 — and it does what visitors flying in without a plan actually need: an itinerary assembled from the operators who run the trips, with transport, guides and beds booked in one go.
They sell self-drive tours as well as guided circuits, and take groups. If you want the Maroni, Kaw and the Îles du Salut inside a fortnight and no appetite for arranging six separate boats, this is the shortcut.