São Vicente is served by Cesária Évora Airport (VXE), named after the island's most famous daughter. International flights connect to Lisbon (TAP, several times a week) and Amsterdam (TUI), and there are connections to other Cape Verde islands. Inter-island flights on TACV Cabo Verde Airlines or Binter Canarias connect São Vicente to Santiago (Praia), Sal, and other islands.
By sea, inter-island ferries connect Mindelo to other islands. The most important is the crossing to Santo Antão — the ferry from Porto Grande in Mindelo to Porto Novo takes around 50 minutes and runs several times daily. There is also a weekly passenger/cargo ferry service that loops through the other islands.
Within Mindelo, taxis are plentiful and cheap. Aluguers (shared minibuses) run between Mindelo and the main beaches and villages around the island at low cost.