Lochem is on the railway line between Zutphen and Hengelo — direct trains link it to both cities in around 20 minutes, and further connections from Zutphen reach Arnhem and Apeldoorn quickly. From Amsterdam, allow about 1 hour 45 minutes with one change at Zutphen or Deventer.
By road, Lochem sits a few kilometres off the A1 and the N346. Cars from anywhere in the central or western Netherlands can reach it in under two hours.