Tarancón sits on the A-3 motorway between Madrid and Valencia, about 80 kilometres south-east of Madrid and 270 km north-west of Valencia. By car the trip from Madrid takes a little over an hour.
The town is also served by frequent ALSA buses on the Madrid–Valencia and Madrid–Albacete lines, with the bus station a short walk from the centre. There is no longer a passenger rail service; the old station closed when the AVE high-speed line bypassed the town. If you are travelling between Madrid and Cuenca or Valencia and want a coffee stop, Tarancón is the sensible place to do it.