Titusville is reached by car. I-95 runs along the western edge of town with three exits, and US 1 runs through the centre as the main north-south street. Orlando International Airport (MCO) is the closest major airport, about 50 minutes west by car. Daytona Beach (DAB) is 45 minutes north.
For launches, plan to arrive several hours early — Titusville's grid is small and the riverfront roads close to traffic during major missions. There is no commercial rail or bus service into Titusville beyond a few daily Greyhound runs.