The Louis Bolduc House (c. 1792) is the finest surviving example of French Creole colonial architecture in the United States and the centerpiece of Ste. Genevieve's historic district. It was built using the distinctive poteaux-sur-solle technique: heavy oak posts set vertically into a timber sill, with the spaces between filled with bousillage — a mixture of mud, straw, and horsehair that hardened like cement. The steep Norman hip roof with its hand-hewn trusses was designed to shed snow and rain away from the wide surrounding gallery.
The house is now a National Historic Landmark and operates as a museum furnished with period pieces, including original Bolduc family items. Visitors can examine the construction methods up close — the bousillage is visible in the walls, and the structure's differences from American timber-frame or brick construction are immediately apparent. The grounds include a reconstructed stockade fence, a colonial kitchen garden, and a detached kitchen building typical of the era.