Hamilton sits about 30 miles north of Cincinnati, making Cincinnati/Northern Kentucky International Airport (CVG) the most practical air gateway. From the airport, the drive to Hamilton takes about 45 minutes via I-75 North.
By car from Cincinnati, take I-75 North to US-127 North. There is no direct passenger rail service to Hamilton; Amtrak serves Cincinnati, where you would need to rent a car or arrange a ride. Greyhound operates bus service to the region.