The Museo Arqueologico Regional gives Neiva a compact introduction to the pre-Hispanic cultures of Huila. Its collection is especially useful if you are heading onward to San Agustin or the Magdalena valley and want some context before seeing larger archaeological landscapes.
The museum is not a replacement for the region's great outdoor sites, but it fills an important gap in the city. Expect a focused visit rather than a long museum afternoon: ceramics, stone pieces, and interpretive material that connect Neiva to the wider archaeology of southern Colombia.