Getting around Guinea requires patience. There are no functioning railways, no reliable bus network, and road conditions range from tolerable to appalling depending on the season.
Bush taxis are the backbone of intercity travel. These are typically old Peugeot 504s or minivans that depart when full -- which can mean hours of waiting at the gare routiere. They cover all major routes: Conakry to Labe, Conakry to Kankan, and so on. Fares are fixed by route but always confirm before boarding. The ride from Conakry to Labe takes roughly 6-8 hours on a good day.
In Conakry, shared taxis are the standard way to get around. They run fixed routes and you flag them down on the street. Motorcycle taxis (motos) are faster but riskier. Ride-hailing apps Yango and Heetch have gained a foothold in the capital and offer a more comfortable alternative with upfront pricing.
Domestic flights between Conakry and a few regional cities (Kankan, Labe) exist on paper but schedules are unreliable. Do not count on them.
Roads deteriorate dramatically outside the main paved corridors. The road from Conakry to Labe is tarmac and in reasonable condition. Beyond that, many routes are laterite tracks that become mud baths in the rainy season (June to October). During the rains, travel times can double or triple, and some roads become impassable entirely.
Hiring a car with driver is possible through hotels and travel agencies in Conakry. This is expensive by local standards but gives you flexibility and saves considerable time. Self-driving is not recommended unless you are experienced with West African road conditions.