Offenbach is part of the Frankfurt Rhine-Main S-Bahn network and is effectively a suburb of Frankfurt in transport terms. S-Bahn lines S1, S2, S8, and S9 all pass through Offenbach Hauptbahnhof, connecting to Frankfurt Hauptbahnhof in about 15 minutes. The journey from Frankfurt Airport takes about 40 minutes on the S-Bahn.
By car from Frankfurt city centre, cross the river via the Deutschherrnbrücke or Ignatz-Bubis-Brücke — the city is less than 10 km east of Frankfurt centre. Driving is the less pleasant option given parking constraints in the city centre.