Lippstadt has a direct train station on the Mid-Germany Railway (Mitte-Deutschland-Verbindung), with regular services to Dortmund (about 55 minutes) and Paderborn (about 35 minutes). Connections are frequent — around 28 trains per day between Lippstadt and Paderborn alone on weekdays — making the town easy to reach from either direction without a car.
By car, Lippstadt sits on the B55 road, roughly 30 km west of Paderborn and 60 km east of Dortmund. The nearest regional airport is Paderborn/Lippstadt Airport (IATA: PAD), about 15 km north of the town, with flights to a limited number of German and European destinations.