Enniskerry is about 24 kilometres from Dublin city centre. The most direct public transport option is bus route 185 from Bray, which is itself easily reached from Dublin by DART (suburban rail). The 185 takes about 20 minutes from Bray and runs frequently enough for a day trip.
By car from Dublin, take the N11 south towards Bray and turn off at Kilpedder or Kilmacanogue; the drive takes 35-45 minutes depending on Dublin traffic. Parking is available in the village and at the Powerscourt Estate entrance. Cyclists use the route from Bray along the back roads through Killarney — a pleasant and not too demanding ride of about 10 kilometres.