Biomuseo is Panama City's most visually striking museum, a bright Frank Gehry building on the Amador Causeway. Its exhibitions explain why the rise of the Isthmus of Panama mattered globally, changing oceans, climates, migration routes, and biodiversity across the Americas.
The museum pairs naturally with a walk or bike ride along the causeway. It is especially good early in a Panama trip, because it gives context for the country's forests, coasts, canal landscape, and role as a biological bridge.