Bluff has no public transport. A car is essential. The nearest commercial airports are in Moab (Grand County Airport, 1.5 hours north), Cortez, Colorado (about 1.5 hours east), and Grand Junction, Colorado (3 hours east). Most visitors drive in from US-191 (running between Moab and the Arizona border) or US-163 from Monument Valley.
The nearest full-service town is Cortez, Colorado, about 90 minutes east — worth stocking up on supplies and fuel before heading to Bluff, as options in town are limited.