Misamis Occidental is a province near the narrow strip of land linking northwestern Mindanao to the north-central part of the island. It is bounded by the Mindanao Sea to the northeast, Iligan Bay to the east, Panguil Bay to the southeast, and the provinces of Zamboanga del Norte and del Sur to the west.
With three of its boundaries formed by water, fishing is one of the main industries. The terrain beyond the coastal areas is hilly and rolling, becoming particularly rugged towards the western border, where the wide bulk of Mount Malindang rises through montane forest to 2425 metres.
The province's three cities each have a distinct character: Ozamiz on the southern channel is the busiest, with the Spanish-era Cotta Fort on the seafront; Oroquieta is the provincial capital; and Tangub, at the southern end, is known nationally for its December Christmas Symbols Festival and for the panoramic Hoyohoy Highland park behind the city. On the northern coast, the white sand and mangrove boardwalks of Baliangao are the most rewarding place to swim.