Trpanj sits at the quiet north-western end of the Pelješac peninsula, and the whole peninsula opens up from here. The obvious excursion is inland into the wine country: the southern slopes around Potomje, Trstenik, and Janjina are the home of Dingač and Postup, Croatia's most celebrated reds, made from the Plavac Mali grape on near-vertical, sun-baked terraces above the sea.
A loop drive from Trpanj takes a half-day, threading through the Potomje tunnel to the seaward vineyards and stopping at a handful of family cellars — tastings are generally informal and possible without booking outside the busiest weeks of August. From the same road you can carry on down the spine of the peninsula toward Orebić and the captains' houses, or catch the ferry across to Ploče on the mainland for a longer push toward the Neretva delta.