The old town inside the line of the former walls is small enough to cover entirely on foot in an afternoon. Most of the streets are pedestrianised or low-traffic.
For the salt pans, the Stagnone lagoon, and the wine cellars on the road south, you really need a car or a bicycle — public transport is sparse. A small ferry from Contrada Spagnola crosses the lagoon to the island of Motya every half hour in season.