Hengelo has good rail connections. Direct trains run from Amsterdam Centraal (approximately 1h40), Utrecht (1h20), and Deventer (35 minutes). The station is central and walkable to most of the city's attractions. From Germany, direct trains connect through Bad Bentheim to Hengelo from the Rheine area.
By car, Hengelo sits on the A35 motorway connecting Almelo and Enschede. The journey from Amsterdam takes about 1h45 by road.