Villa Florida is a small town on the Río Tebicuary, about 160km south of Asunción on the road to Encarnacion. It's known primarily for sport fishing — the river here is popular with dorado and surubí anglers, particularly between August and November. Several fishing lodges operate along the river and cater to fishing tourists from Asunción and abroad.
Outside fishing season the town sees little traffic and there's not much to detain a passing traveller, though the river scenery is pleasant enough for a lunch stop en route south.