Landau has its own railway station (Landau (Pfalz) Hauptbahnhof) with direct regional services to Neustadt an der Weinstraße, Karlsruhe, and Wissembourg in Alsace. From Karlsruhe, connections to Frankfurt, Stuttgart, and beyond are straightforward. Journey time from Karlsruhe is about 45 minutes.
By car, Landau is reached via the A65 Autobahn from Ludwigshafen or via the B10 from the east. The nearest major airports are Frankfurt (about 130 km) and Stuttgart (about 140 km). The Strasbourg airport in France is about 90 kilometres to the south and may be useful for international connections.