Accra is bigger and more spread out than it first appears, and getting from one neighbourhood to another can mean an hour stuck in traffic. Walking is fine within Osu, Jamestown, or the Independence Square axis, but you'll need wheels for almost everything else.
Taxis are everywhere — yellow-fronted, mostly without meters. Agree the fare before getting in; a short hop within town should be a few cedis, a longer cross-town ride more. Bolt and Uber both work in Accra and remove the bargaining entirely; both are usually the cheapest option.
Tro-tros — battered minibuses crammed to twenty-plus passengers — are how most Ghanaians get around. Routes are fixed, fares are tiny, the mate hangs out the door shouting the destination. They're slow, hot, and an experience worth having at least once.
Driving yourself in Accra is not recommended. The traffic is brutal, signage is poor, and parking is a problem. If you must, hire a car with a driver.