Juanito's, on the main highway through the Santiago hotel zone, has been a Manzanillo institution since 1977 and remains the easiest first stop for visitors looking for familiar food after a long flight. The menu is the standard Mexican-American repertoire — burgers, sandwiches, pancakes, fish tacos — done well, in big portions and at fair prices.
It is open from breakfast to late, has reliable wifi and decent margaritas, and is busy with both locals and tourists. Not the most adventurous meal in town, but a useful safety net.