La Moneda Cultural Center sits beneath the plaza beside the presidential palace, which makes it an easy stop while exploring Santiago Centro. Its galleries host changing art, photography, history, and design exhibitions, with enough variety that the visit depends on what is showing.
The building is modern, calm, and useful on a hot or rainy day. There is also a shop for Chilean crafts and design pieces, plus a cafe if you want a break between the palace area and the museums around the Plaza de Armas.