Helligåndshuset is Randers' best medieval building, a well-preserved Gothic brick structure from around 1490 that served as a hospital and almshouse for the poor and sick of the medieval town. The building survived the fires and redevelopments that swept most of Randers' older structures because it was continuously in use and maintained by successive owners.
The exterior is the main attraction — characteristic Jutland Gothic brickwork with the precision and decorative restraint typical of the region. The building is occasionally open for events and exhibitions; at other times the exterior and the setting in the old town can be appreciated freely. Combined with Sankt Mortens Kirke a few minutes' walk away, the Helligåndshuset gives a clear sense of how significant a medieval town Randers was before the economic dominance of the western Jutland ports.