The Museo Regionale Agostino Pepoli occupies the former Carmelite convent attached to the Santuario dell'Annunziata at the eastern end of Trapani's old city. The museum was established in the early 20th century and contains a wide-ranging collection of Sicilian art and craft from the medieval period through the 19th century. The building itself — a 14th-century cloister with arched galleries — is worth seeing.
The collection is strong on Sicilian painting and sculpture from the 15th–17th centuries, with works by artists from the Trapani and Palermo schools. The decorative arts section, particularly the coral-work room, is exceptional — the intricacy of the carved coral objects and their settings in precious metals shows what the craftsmen of this region were capable of at the height of the trade. The museum also has a good collection of Sicilian majolica ceramics and a section on local numismatics and archaeological finds.