A 16th-century parish church on the Plaza de San Andrés, notable for its attached Chapel of San Isidro — Madrid's patron saint is buried in a separate crypt connected to the church. The chapel (added in the 17th century by Pedro de la Torre) has an exceptionally ornate Baroque cupola and houses the relics of the saint, which become the focus of the annual Fiestas de San Isidro each May.
The church was badly damaged in the Civil War and subsequently restored. The exterior facing the plaza is one of the more atmospheric corners of La Latina — particularly early on Sunday mornings before the Rastro crowds arrive. Free entry. Metro La Latina.